徐效华
徐效华
博士 教授
徐效华,博士,教授,元素有机化学研究所,毕业于中山大学,安徽芜湖人。
工作内容:教学科研
人才称号:
通讯地址:天津市卫津路94号南开大学元素有机化学研究所
电 话:02223508871
电子邮件:xiaohuaxu@nankai.edu.cn
课题组网站:
研究领域:研究方向:生态功能天然产物,基于生态化学品设计合成农用化学品,植物化感作用
教育及科研经历:

1983-1987年 安徽师范大学大学化学系本科

1987-1990年 南开大学元素所研究生

1990-1992年 天津药业公司工作

1992-1995中山大学化学系博士生

1995-1997南开大学化学博士后

1997-2002南开大学元素所副教授

2002-香港中文大学化学助理研究员

2002-至今南开大学化学院教授

荣誉和奖励


科研成果与代表作

在国内外刊物发表80篇学术论文。申请专利19项,授权专利4项。获得天津市科学技术二等奖和中国植物保护学会科学技术二等奖。

代表论文:

1 Iridium-Catalyzed Asymmetric Hydrogenation of 2?Pyridyl Cyclic Imines: A Highly Enantioselective Approach to Nicotine Derivatives C. Guo, D.-W. Sun, S. Yang, S.-J. Mao, X.-H. Xu*, S.-F.i Zhu*, and Q.-L. Zhou* J. Am. Chem. Soc. 2015, 137, 90?93

2 Diastereoselection during 1,2-addition of 3-bromomethyl-5H-furan-2-one to ?- chiral aldehydes mediated by indium in aqueous and organic solvent systems: Direct route to obtain optically ?-methylene-?-butyrolactones. F.-H. Zhang, Y. Liu, L.G. Xie and X. H.Xu RSC. Advances,2014,4,17218.

3. Enantioselective Palladium-Catalyzed Ring-Opening Reaction of Azabenzonorbornadienes with Methyl 2-Iodobenzoate: An Efficient Access to cis-Dihydrobenzo[c]phenanthridinones K.-L. Huang, C. Guo, L.-J. Cheng, L.-G. Xie, Q.-L. Zhou, X.-H. Xu ,* and S.-F. Zhu Adv. Synth. Catal. 2013, 355, 2833 – 2838

4 Palladium-catalyzed annulation reactions of methyl-o-halobenzoates with azabicyclic alkenes: a general protocol for the construction of benzo[c]phenanthridine derivatives C. Guo, K.-L. Huang, L.-G. Xie, X.-H. Xu * RSC Adv., 2013, 3, 17271–17280

5 Pd-catalyzed diastereoselective allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-r-butyrolactones with a syn configuration F.H. Zhang, Y.X. Yang, L.G Xie and X.H. Xu* Chem. Commun., 2013, 49, 4697—4699

6. Synthesis and Herbicidal Potential of Substituted Aurones M.zhang,X.-H. Xu * C.-H.Kong Pest Management Science 2012,68,1512-1522

7. Zinc and indium-mediated Barbier-type allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: an efficient synthesis of α-methylene-γ-butyrolacton Y.-Z Gao,X. Wang,L.- D Sun,L.-G.Xie and X.-H Xu* Org. Biomol. Chem., 2012, 10, 3991-3998

8. Palladium-Catalyzed Tandem Reaction to Construct Benzo[c]phenanthridine: Application to the Total Synthesis of Benzo[c]phenanthridine alkaloids P.Lv, K.-L Huang, L.-G. Xie and X.-H. Xu* Org. Biomol. Chem., 2011, 9, 3133-3135

9 Concise Total Synthesis of (?)-8-Epigrosheimin H.-S Yang, Y.-Z. Gao, X.-X Qiao, L.-G. Xie, and X.-H Xu* Org. Lett., 2011, 13 (14), 3670–3673

10. Allelochemical tricin in rice hull and its aurone isomer against rice seedling rot disease. C.-H.Kong, X.-H. Xu, M. Zhang, S.-Z. Zhang Pest Management Science, 2010 ,66 (9): 1018-1024.

人才培养
已经培养硕士毕业生16人,博士毕业6名
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