工作内容：教学科研
人才称号：青年学术带头人
通讯地址：天津市南开区卫津路94号南开大学化学学院
电 话：
电子邮件：jtdong2025@nankai.edu.cn
课题组网站：https://panglab.nankai.edu.cn/info/1023/1020.htm
研究领域：
1.基于微流控芯片的病原微生物及细胞外囊泡分析
2.基于动态核酸自组装的仿生、传感与成像系统
3.基于微/纳米材料靶向递送的精准医学分析
2010－2014，山东大学，化学基地专业，理学学士
2014－2021，北京大学，分析化学专业，理学博士
2017－2019，美国加州大学洛杉矶分校，联合培养
2021－2025，以色列耶路撒冷希伯来大学，博士后
2025年至今，南开大学化学学院，研究员/博导
近年来，已在微流控分析、核酸动态仿生系统和生物医学检测领域以第一/通讯作者（含共同）接收/发表SCI 论文20余篇，包括Nat. Chem.（1篇），J. Am. Chem. Soc.（4篇），Sci. Adv.（2篇），Angew. Chem. Int. Ed.（2篇），Nat. Commun.（1篇），Adv. Mater.（1篇），Chem. Soc. Rev.（1篇），ACS Nano（2篇），Adv. Funct. Mater.（1篇）等期刊。
1. J. Dong, I. Willner*, Dynamic Transcription Frameworks, Nat. Chem., 2025, in press.
2. J. Dong, F. Xia*, F. Huang*, and I. Willner*, Dynamic Transcription Machineries in Protocells, J. Am. Chem. Soc., 2025, 147, 22, 18359–18373.
3. J. Dong, I. Willner*, Photochemically Triggered, Transient, and Oscillatory Transcription Machineries Guide Temporal Modulation of Fibrinogenesis, J. Am. Chem. Soc., 2025, 147, 2216–2227.
4. J. Dong, I. Willner*, Transient Transcription Machineries Modulate Dynamic Functions of G-Quadruplexes: Temporal Regulation of Biocatalytic Circuits, Gene Replication and Transcription, Angew. Chem. Int. Ed., 2023, 62, e202307898.
5. J. Dong, Y. J. Jan, J. Cheng, R. Y. Zhang, M. Meng, M. Smalley, P.-J. Chen, X. Tang, P. Tseng, L. Bao, T.-Y. Huang, D. Zhou, Y. Liu, X. Chai, H. Zhang, A. Zhou, V. G. Agopian, E. M. Posadas, J.-J. Shyue, S. J. Jonas, P. S. Weiss, M. Li*, G. Zheng*, H.-h. Yu*, M. Zhao*, H.-R. Tseng*, and Y. Zhu*, Covalent Chemistry on Nanostructured Substrates Enables Noninvasive Quantification of Gene Rearrangements in Circulating Tumor Cells, Sci. Adv., 2019, 5, eaav9186.
6. J. Dong#, J.-F. Chen#, M. Smalley, M. Zhao, Z. Ke*, Y. Zhu*, and H.-R. Tseng*, Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications, Adv. Mater., 2020, 32, 1903663.
7. J. Dong, M. P. O’ Hagan, and I. Willner*, Switchable and Dynamic G-Quadruplexes and Their Applications, Chem. Soc. Rev., 2022, 51, 7631–7661.
8. J. Dong, I. Willner*, Dynamic Transcription Machineries Guide the Synthesis of Temporally Operating DNAzymes, Gated and Cascaded DNAzyme Catalysis, ACS Nano, 2023, 17, 687–696.
9. M. Ji, J. Dong*, Z. Ye, J. Kang, G. Han, X. Hong, Y, Wei, X, Chen*, W. Sun*, and D. Liu*, Endogenous HClO-Gated Cascade MicroRNA Imaging for Precise Diagnosis of Atherosclerosis In Vivo, J. Am. Chem. Soc., 2025, 147, 7113–7126. (*co-corresponding author)
10. X. Wang, J. Dong*, J. Kang, X. Chen, X. Hong, J. Chen, W. Du, H. Cai, and D. Liu*, Self-Adaptive Release of Stem Cell-Derived Exosomes from a Multifunctional Hydrogel for Accelerating MRSA-Infected Diabetic Wound Repair, J. Am. Chem. Soc., 2025, 147, 16362–16378. (*co-corresponding author)
人才培养
课题组每年招收博士生2名，硕士生2名，博士后若干名。热烈欢迎具有化学、材料、生物、医学等背景的科研人才加入我们团队。
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