Home  Chinese  

Position: Home >> Research >> Achivements

Synthesis of Natural Products

Prof. Jianhua Xie has developed several highly efficient catalytic asymmetric hydrogenation of ketones via dynamic kinetic resolution (DKR) with chiral spiro ruthenium and iridium catalysts for the synthesis of chiral alcohols with contiguous stereocenters. Using these catalytic methodologies several natural products including bioactive alkaloids such as (-)-galanthamine, (-)-mesembrine, (+)-hapalindole Q, and terpenoids such as (-)-hamigeran B were synthesized in high efficiency and enantioselectivity.