尹学博
尹学博

博士 教授

中心主任

尹学博,博士,教授,分析科学研究中心,中心主任,毕业于南开大学,河北邢台新河县人。
工作内容:教学科研
特殊人才称号:教育部新世纪优秀人才
通讯地址:天津市卫津路94号南开大学中心实验室
电 话:(86) 22 23501380
电子邮件:xbyin@nankai.edu.cn
课题组网站:
研究领域:

传感与成像

多功能探针合成及传感、成像及诊疗一体化应用

招生学科:分析化学

教育及科研经历:

河北师范学院(本科) 1988.9-1992.7

河北新河县振堂中学(教师) 1992.7-1997.9

抚顺石油学院(硕士) 1997.9-2000.7

南开大学(博士) 2000.9-2003.7

中科院长春应用化学研究所(博士后) 2003.8-2005.7

南开大学 化学学院(副教授) 2005.7-2010.12

南开大学 化学学院(教授) 2011.1-至今

荣誉和奖励

教育部新世纪优秀人才(2006)

南开大学教学成果二等奖(排名第一,2013)

中国分析测试协会科学技术奖二等奖(排名第一,2015)

南开大学教学成果二等奖(排名第一,2017)

科研成果与代表作

长期从事分析化学新方法研究,相关成果发表SCI收录论文107篇,包括Acc. Chem. Res., J. Am. Chem. Soc., Adv. Funct. Mater., Small, Chem. Sci., Anal. Chem., ACS Appl. Mater. Interfaces, TrAC-Trends Anal. Chem., 和Biosens. Bioelectron.等分析化学及相关学科期刊等,H指数43。近年来,结合材料科学的最新研究成果,开展肿瘤的成像和和原位治疗等相关研究。详细研究了碳点的新颖制备,发光机理及双模态成像应用。充分利用金属有机骨架材料的可设计性特点,通过简便、易得的功能配体和金属节点,设计制备了功能化金属有机骨架材料,提出多发光的概念,发展了系列多发光金属有机骨架的设计策略,开展金属有机骨架多模态成像及诊疗一体化应用。


代表性论文

(1)Yin, H.-Q.; Yin, X.-B.* Metal–Organic Frameworks with Multiple Luminescence Emissions: Designs and Applications. Acc Chem Res 2020, 53, 485-495.

(2)Yin, H.-Q.; Wang, X.-Y.; Yin, X.-B.* Rotation Restricted Emission and Antenna Effect in Single Metal–Organic Frameworks. J Am Chem Soc 2019, 141, 15166-15173.

(3)Cheng, Y.; Wen, C.; Sun, Y.-Q.; Yu, H.; Yin, X.-B.* Mixed-Metal MOF-Derived Hollow Porous Nanocomposite for Trimodality Imaging Guided Reactive Oxygen Species-Augmented Synergistic Therapy. Adv Funct Mater 2021, 31, 2104378.

(4)Wang, Y.-M.; Liu, W.; Yin, X.-B.* Self-Limiting Growth Nanoscale Coordination Polymers for Fluorescence and Magnetic Resonance Dual-Modality Imaging. Adv Funct Mater 2016, 26, 8463-8470.

(5)Chen, F.; Wang, Y.-M.; Guo, W.; Yin, X.-B.* Color-tunable lanthanide metal–organic framework gels. Chemical Science 2019, 10, 1644-1650.

(6)Wang, Y.-M.; Liu, W.; Yin, X.-B.* Multifunctional mixed-metal nanoscale coordination polymers for triple-modality imaging-guided photodynamic therapy. Chemical Science 2017, 8, 3891-3897.

(7)Yang, J.-C.; Shang, Y.; Li, Y.-H.; Cui, Y.; Yin, X.-B.* An “all-in-one” antitumor and anti-recurrence/metastasis nanomedicine with multi-drug co-loading and burst drug release for multi-modality therapy. Chemical Science 2018, 9, 7210-7217.

(8)Yin, H.-Q.; Yin, F.; Yin, X.-B.* Strong dual emission in covalent organic frameworks induced by ESIPT. Chemical Science 2019, 10, 11103-11109.

(9)Liu, W.; Wang, Y. M.; Li, Y. H.; Cai, S. J.; Yin, X. B.*; He, X. W.; Zhang, Y. K. Fluorescent Imaging-Guided Chemotherapy-and-Photodynamic Dual Therapy with Nanoscale Porphyrin Metal Organic Framework. Small 2017, 13, 1603459.

(10)Tian, X.-T.; Yin, X.-B.* Carbon Dots, Unconventional Preparation Strategies, and Applications Beyond Photoluminescence. Small 2019, 15, 1901803.

(11)Sun, Y.-Q.; Cheng, Y.; Yin, X.-B.* Dual-Ligand Lanthanide Metal–Organic Framework for Sensitive Ratiometric Fluorescence Detection of Hypochlorous Acid. Anal Chem 2021, 93, 3559-3566.

(12)Wang, Y.-M.; Yang, Z.-R.; Xiao, L.; Yin, X.-B.* Lab-on-MOFs: Color-Coded Multitarget Fluorescence Detection with White-Light Emitting Metal–Organic Frameworks under Single Wavelength Excitation. Anal Chem 2018, 90, 5758-5763.

(13)Xu, Y.; Jia, X.-H.; Yin, X.-B.*; He, X.-W.; Zhang, Y.-K. Carbon Quantum Dot Stabilized Gadolinium Nanoprobe Prepared via a One-Pot Hydrothermal Approach for Magnetic Resonance and Fluorescence Dual-Modality Bioimaging. Anal Chem 2014, 86, 12122-12129.

(14)Yang, Z.-R.; Wang, M.-M.; Wang, X.-S.; Yin, X.-B.* Boric-Acid-Functional Lanthanide Metal–Organic Frameworks for Selective Ratiometric Fluorescence Detection of Fluoride Ions. Anal Chem 2017, 89, 1930-1936.

(15)Yin, H.-Q.; Yang, J.-C.; Yin, X.-B.* Ratiometric Fluorescence Sensing and Real-Time Detection of Water in Organic Solvents with One-Pot Synthesis of Ru@MIL-101(Al)–NH2. Anal Chem 2017, 89, 13434-13440.

人才培养

毕业博士研究生4名,硕士研究生15名,在读博士研究生5,硕士研究生2名,访问学者1名(王诗文)

3人获南开大学研究生奖学金二等奖(沙蓓蓓,魏玮,刘东元)

4人获南开大学研究生奖学金三等奖(辛有英,刘东元,唐春霞,卜楠楠)

3人获南开大学优秀硕士论文(沙蓓蓓,刘东元,唐春霞)

1人获天津市优秀硕士论文(唐春霞)


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