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郭玮炜
2020-05-25  

郭玮炜

国家“万人计划”青年拔尖人才

学科专业
分析化学
通讯地址
天津市卫津路94号南开大学化学楼南楼303室
联系电话
(+86) 15822298109
电子邮件
weiweiguo@nankai.edu.cn
网站地址
研究领域
智能生化分析
功能DNA水凝胶
荧光纳米探针
DNA纳米技术

教育及科研经历
1999.09-2003.07 吉林大学化学学院 理学学士

2004.09-2010.07 中科院长春应化所电分析国家重点实验室 理学博士 (导师:汪尔康院士)

2010.08-2011.10 中科院长春应化所电分析国家重点实验室 研究助理

2011.11-2015.11 以色列耶路撒冷希伯来大学 化学所 博士后 (合作导师:Itamar Willner 教授)

2015.11至今南开大学化学学院 研究员 博士生导师

荣誉和奖励
2015年 南开大学百名青年学术带头人培养计划

2019年 第四批国家“万人计划”青年拔尖人才

科研成果与代表作
郭玮炜研究员致力于发展智能的生化分析方法和传感装置,集中研究具备多功能可编码的DNA传感材料包括DNA水凝胶与纳米结构等传感材料及结合纳米簇、量子点和功能二维结构等的复合功能传感材料的设计、调控及相关基础科学问题,建立和发展针对不同类型生化分析目标的分离检测新原理与新方法,进而发展智能的生化分析试纸与芯片、穿戴式生化传感器和植入式诊疗一体化系统,目前已经取得了一系列创新研究成果,发表SCI论文40余篇,总引用次数超过2400次,H-index为 27。其中,以第一(共同第一)或通讯作者发表SCI论文20余篇,包括2篇《J. Am. Chem. Soc.》,2篇《Angew. Chem. Int. Ed.》,3篇《Adv. Mater.》,2篇《Adv. Funct. Mater.》,2篇《Small》,1篇《Chem. Sci.》等高影响力SCI收录学术杂志论文,最高单篇他引超过380次,多篇学术论文被评为ESI高被引论文(Highly Cited Papers)。此外,担任中文核心期刊《分析试验室》编委(第五届),及担任Angew. Chem. Int. Ed., Adv. Mater., Chem. Sci., ACS Nano, ACA等Wiley/ACS/RSC/Elsevier出版社旗下十多个业界公认的国际顶级或高水平学术期刊的独立通讯评审人和仲裁评审。目前,已先后主持国家自然科学基金青年与面上项目、天津市自然科学基金重点项目以及南开大学百青项目等多项。

Selected Publications:

(1) Fengyun Li, Danya Lyu, Shuo Liu, Weiwei Guo*, DNA Hydrogels and Microgels for Biosensing and Biomedical Applications, Adv. Mater. 2020, 32, 1806538.
(2) Chunyan Wang, Fengyun Li, Yanhui Bi, Weiwei Guo*, Reversible Modulation of Two-Dimensional Photonic Crystals with a Responsive Shape-Memory DNA Hydrogel Film, Adv. Mater. Interfaces 2019, 6, 1900556.
(3) Danya Lyu, Jing Li, Xiaowen Wang, Weiwei Guo*, and Erkang Wang*, Cationic Polyelectrolyte Modified Fluorescent DNA-Silver Nanoclusters for Rapid Bioimaging with Enhanced Emission and Higher Stability, Anal. Chem. 2019, 91, 2050-2057.
(4) Yanhui Bi, Cuiyan Han, Weiwei Guo*, Smart DNA Hydrogels for Biosensing Applications, Sci Sin Chim, 2019, 49: 766-775.
(5) Fengyun Li, Qi Gao, Mingjie Yang, Weiwei Guo*, Regulation of Catalytic DNA Activities with Thermosensitive Gold Nanoparticle Surfaces, Langmuir, 2018, 34, 14932-14939.
(6) Shuo Liu, Weiwei Guo*, Anti-Biofouling and Healable Materials: Preparation, Mechanisms, and Biomedical Applications, Adv. Funct. Mater. 2018, 28, 1800596.
(7) Jingrun Ran, Weiwei Guo*, Hailong Wang, Bicheng Zhu, Jiaguo Yu, Shi-Zhang Qiao*, Metal-Free 2D/2D Phosphorene/g-C3N4 Van der Waals Heterojunction for Highly Enhanced Visible-Light Photocatalytic H2 Production, Adv. Mater. 2018, 30, 1800128 (ESI高被引论文).
(8) Shanshan Chen, Danya Lyu, Tao Ling, Weiwei Guo*, Reversible Modulation of CsPbBr3 Perovskite Nanocrystal/gold Nanoparticle Heterostructures, Chem. Commun. 2018, 54, 4605--4608.
(9) Jingtao Wang(#), Pingping Chen(#), Benbing Shi, Weiwei Guo*, Mietek Jaroniec, Shi-Zhang Qiao*, Regularly Channeled Lamellar Membrane for Unparalleled Water and Organics Permeation, Angew. Chem. Int. Ed. 2018, 57, 6814-6818 (封面文章).
(10) Fengyun Li, Chunyan Wang, and Weiwei Guo*, Multifunctional Poly-N-Isopropylacrylamide/DNAzyme Microgels as Highly Efficient and Recyclable Catalysts for Biosensing, Adv. Funct. Mater. 2018, 28, 1705876.
(11) Danya Lyu, Shanshan Chen, Weiwei Guo*, Liposome Crosslinked Polyacrylamide/DNA Hydrogel: a Smart Controlled-Release System for Small Molecular Payloads, Small 2018, 14, 1704039.
(12) Weiwei Guo(#), Chun-Hua Lu(#), Ron Orbach, Fuan Wang, Xiu-Juan Qi, Alessandro Cecconello, Dror Seliktar, Itamar, Willner*, pH-Stimulated DNA Hydrogels Exhibiting Shape-Memory Properties, Adv. Mater., 2015, 27, 73-78.
(13) Chun-hua Lu(#), Weiwei Guo (#), Yuwei Hu, Xiu-Juan Qi, Itamar Willner*, Multi-Triggered Shape-Memory Acrylamide-DNA Hydrogels, J. Am. Chem. Soc., 2015, 137, 15723–15731.
(14) Weiwei Guo(#), Chun-Hua Lu(#), Xiu-Juan Qi, Ron Orbach, Michael Fadeev, Huang-Hao Yang, Itamar Willner*, Switchable Bifunctional Stimuli-Triggered Poly-N-Isopropylacrylamide/DNA Hydrogels, Angew. Chem. In. Ed. 2014, 53, 10134 –10138. (VIP文章)
(15) Weiwei Guo, Jipei Yuan, Qingzhe Dong, Erkang Wang*, Highly sequence-dependent formation of fluorescent silver nanoclusters in hybridized DNA duplexes for single nucleotide mutation identification, J. Am. Chem. Soc., 2010, 132, 932-934. (ESI 高被引论文)
(16) Chun-hua Lu(#), Weiwei Guo (#), Xiu-Juan Qi, Avner Neubauer, Yossi Paltiel, Itamar, Willner*, Hemin-G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline, Chem. Sci. 2015, 6, 6659-6664.
(17) Weiwei Guo(#), Ron Orbach(#), Iris Mironi-Harpaz, Dror Seliktar, Itamar Willner*, Fluorescent DNA hydrogels composed of nucleic Acid-stabilized silver nanoclusters, Small, 2013, 9, 3748-3752.
(18) Weiwei Guo(#), Xiu-Juan Qi(#), Ron Orbach, Chun-hua Lu, Lina Freage, Iris Mironi-Harpaz, Dror Seliktar, Huang-Hao Yang, Itamar Willner, Chem. Commun., 2014, 50, 4065-4068.
(19) Ron Orbach(#), Weiwei Guo(#), Fuan Wang, Oleg Lioubashevski, Itamar Willner*, Self-Assembly of Luminescent Ag Nanocluster-Functionalized Nanowires, Langmuir, 2013, 29, 13066-13071.
(20) Weiwei Guo, Jipei Yuan, Erkang Wang*, Oligonucleotide-stabilized Ag nanoclusters as novel fluorescence probes for the highly selective and sensitive determination of Hg2+ ion, Chem. Commun., 2009, 3395-3397. (ESI 高被引论文)

*: Corresponding author; #: equal first author


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