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周传政
2019-09-09  

周传政

学科专业
化学生物学
通讯地址
天津市卫津路94号南开大学化学理化楼320室
联系电话
022-23497531
电子邮件
chuanzheng.zhou@nankai.edu.cn
网站地址
研究领域
化学生物学
药物化学
有机化学










教育及科研经历
2014 至今 南开大学元素有机化学国家重点实验室
2010-2014 美国约翰霍普金斯大学,博士后 (With Marc M. Greenberg)
2004-2010 瑞典乌普萨拉大学,获得生物有机化学博士学位,导师:Jyoti Chattopadhyaya
2001-2004 南开大学,获得有机化学硕士学位,导师:席真 教授
1997-2001 南开大学,获得理学学士学位,导师:杨华铮 教授











荣誉和奖励
2009 国家优秀自费留学生奖学金




科研成果与代表作
1.F. Guo, Z. Yue, M. Trajkovski, X. Zhou, D. Cao, Q. Li, B. Wang, X. Wen, J. Plavec*, Q. Peng*, Z. Xi and C. Z. Zhou*, Effect of Ribose Conformation on RNA Cleavage via Internal Transesterificatio. J. Am. Chem. Soc., 2018, 140, 11893-11897.
2.Li, F. C.; Zhang, Y. Q.; Bai, J.; Greenberg, M. M.; Xi, Z.; Zhou, C. Z.* 5-Formylcytosine Yields DNA-Protein Crosslinks in Nucleosome Core Particles. J. Am. Chem. Soc. 2017, 139, 10617-10620. [Featured in JACS Spotlights: J. Am. Chem. Soc. 2017, 139, 11629]
3.Zhang, Y. Q.; Zhou, X. P.; Xie, Y. H.; Greenberg, M. M.; Xi, Z. and Zhou, C. Z.* Thiol Specific and Tracelessly Removable Bioconjugation via MichaelAddition to 5?Methylene Pyrrolones. J. Am. Chem. Soc. 2017, 139, 6146?6151. [Recommended by F1000]
4. Zhou, C. Z. and Greenberg, M. M. “DNA Damage by Histone Radicals in Nucleosome Core Particles” J. Am. Chem. Soc. 2014, 136, 6562-6565.
5. Zhou, C.Z., Sczepanski, J. T. and Greenberg, M. M. “Histone modification vis rapid cleavage of C4’-oxidized abasic sites in nucleosome core particles” J. Am. Chem. Soc. 2013, 135, 5274-5277. [Featured in JACS Spotlights: J. Am. Chem. Soc. 2013, 135, 5933]
6. Zhou, C. Z., Sczepanski, J. T. and Greenberg, M. M. “Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles” J. Am. Chem. Soc. 2012, 134, 16734-16741.
7. Zhou, C. Z. and Greenberg, M. M. “Histone catalyzed cleavage of nucleosomal DNA containing 2-deoxyrionolactone” J. Am. Chem. Soc. 2012, 134, 8090?8093. [Featured in JACS Spotlights: J. Am. Chem. Soc. 2012, 134, 9021]
8. Zhou, C. Z.and Chattopadhyaya, J. “Intramolecular Free-Radical Cyclization Reactions on Pentose-Sugars for Synthesis of carba-LNA and carba-ENA and the Application of Their Modified Oligonucleotides as Potential RNA Targeted Therapeutics” Chem. Rev. 2012, 112, 3808-3832.






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