1. 有机合成方法学（复杂多环骨架的高效构筑）：张力环的新型环加成和串联反应；

2. 天然产物全合成；

3．新医药/农药先导发现。

1986-1990：学士，南开大学

1990-1993：硕士，南开大学 

1993-1996：博士，南开大学 

1999-2004：博士后，名古屋大学（日本） ; 肯塔基大学（美国）

2004-: 教授，南开大学化学院元素有机化学研究所

文章更新情况见课题组网站(wzw.nankai.edu.cn)

1. Ding Du, Zhongwen Wang* “A Novel Ring-Opening Based Tandem Domino Process of an Activated Vinyl Cyclopropane” Tetrahedron Lett. 2008, 49, 956-959.

2. Ding Du, Zhongwen Wang* “N-Heterocyclic Carbene-Catalyzed Domino Reactions of Formylcyclopropane 1,1-Diesters: A New Synthesis of Coumarins” Eur. J. Org. Chem. 2008, 4949-4954.

3. Jie Fang, Jun Ren, Zhongwen Wang* “Sc(OTf)3-catalyzed smooth tandem [3+2] cycloaddition/ring opening of donor–acceptor cyclopropane 1,1-diesters with enol silyl ethers” Tetrahedron Lett. 2008, 49, 6659-6662.

4. Bao Hu, Siyang Xing, Zhongwen Wang* “Lewis Acid Catalyzed Ring-Opening Intramolecular Friedel-Crafts Alkylation of Methylenecyclopropane 1,1-Diesters” Org. Lett. 2008, 10(23), 5481-5484

5. Bao Hu, Jianlin Zhu, Siyang Xing, Jie Fang, Ding Du, Zhongwen Wang* “A Highly Site-, Regio-, and Stereoselective Lewis Acid-Catalyzed Formal [3+3] Cycloaddition of Methylenecyclopropane-1,1-Diesters with C,N-Diarylnitrones” Chem. Eur. J. 2009, 15(2), 324-327

6. Ding Du, Linxia Li, Zhongwen Wang* “N-Heterocyclic Carbene-Catalyzed Domino Ring-Opening/Redox Amidation/Cyclization Reactions of Formylcyclopropane 1,1-Diesters: Direct Construction of a 6-5-6 Tricyclic Hydropyrido[1,2-a]indole Skeleton” J. Org. Chem. 2009, 74(11), 4379-4382

7. Yu Bai, Jie Fang, Jun Ren, Zhongwen Wang* “Highly Diastereoselective Gold- or Copper-Catalyzed Formal [4+3] Cycloaddition of 1-(1-Alkynyl) Cyclopropyl Ketones and Nitrones” Chem. Eur. J. 2009, 15(36), 8975-8978

8. Yuexia Bai, Jilai Bao, Jun Ren, Zhongwen Wang* “A modified total synthesis of cystothiazole A” Sci. China Ser. B-Chem 2009, 52(09), 1345-1352

9. Shaojin Chen, Jun Ren, Zhongwen Wang* “A highly regioselective tandem 1,3-dipolar cycloaddition of cyclopropene 1,1-diesters and nitrile oxides: synthesis of highly functionalized isoxazoles” Tetrahedron 2009, 65(45), 9146-9151

10. Bao Hu, Linan Jiang, Jun Ren, Zhongwen Wang* “A n-BuLi-Mediated Expeditious and Stereoselective Ring-Opening Rearrangement of Aryl Methylenecyclopropane 1,1-Diesters” Eur. J. Org. Chem. 2010, 10(7), 1358-1363.

11. Siyang Xing, Wenyan Pan, Chang Liu, Jun Ren, Zhongwen Wang* “Efficient Construction of 

Oxa- and Aza-[n.2.1] Skeletons: Lewis Acid-Catalyzed Intramolecular [3+2] Cycloaddition of 

Cyclopropane 1,1- Diesters with Carbonyls and Imines” Angew. Chem. Int. Ed. 2010, 49(18), 

3215-3218.

12. Bao Hu, Siyang Xing, Jun Ren, Zhongwen Wang* “Total Synthesis of (±)-Bruguierol A via an Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diester” Tetrahedron, 2010, 66(30), 5671-5674.

13. Bao Hu, Jun Ren, Zhongwen Wang* “Lewis acid-catalyzed nucleophilic ring-opening/intramolecular Conia-ene reactions of methylenecyclopropane 1,1-diesters with propargyl alcohols” Tetrahedron 2011, 67(04), 763-768. 

14. Linxia Li, Ding Du, Jun Ren, Zhongwen Wang* “N-Heterocyclic Carbene Catalyzed Domino Reactions of Formylcyclopropane 1,1-Diesters: Construction of a 6-5-5 Tricyclic Pyrrolo[1,2-a]indole” Eur. J. Org. Chem. 2011, (03), 614-618.

15. Jie Fang, Bao Hu, Jun Ren, Zhongwen Wang* “Sc(OTf)3-Catalyzed Tandem [3+2] Cycloaddition/ Nucleophilic Ring-Opening Reaction of Cyclopropane 1,1-Diesters with Azomethine Ylides” Asian J. Chem. 2011, 23(04), 1479-1487.

16. Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren and Zhongwen Wang* “Lewis Acid-Catalyzed Intramolecular Cross [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes with Carbonyls: A General Strategy for Construction of Bridge-Acetal[n.2.1] Skeletons” Angew. Chem. Int. Ed. 2011, 50(52), 12605-12609.

17．Jilai Bao, Jun Ren, Zhongwen Wang* “Synthesis of Substituted Furans through Domino Aldol/Homo-Michael Reactions of Formylcyclopropane 1,1-Diesters with 1,3-Dicarbonyls”Eur. J. Org. Chem. 2012, 2511-2515.

18. Yu Bai, Weijie Tao, Jun Ren and Zhongwen Wang* “Lewis Acid Catalyzed Intramolecular [4+2] and [3+2] Cross-Cycloaddition of Alkynylcyclopropane Ketones with Carbonyl Compounds and Imines” Angew. Chem. Int. Ed. 2012, 51(17), 4112-4116.

19. Zhongwen Wang* “Polar Intramolecular Cross-Cycloadditions of Cyclopropanes toward Natural Product Synthesis” Synlett 2012, 23, 2311-2327

20. Wenju Zhu, Jie Fang, Yong Liu, Jun Ren, Zhongwen Wang* “Lewis Acid Catalyzed Formal Intramolecular [3+2] Cross-Cycloaddition of Cyclopropane 1,1-Diesters with Alkenes: General and Efficient Strategy for Construction of Bridged [n.2.1] Carbocyclic Skeletons” Angew. Chem. Int. Ed. 2013, 52(07), 2032-2037.

21. Zhenjun Wang, Jun Ren, Zhongwen Wang* “Lewis Acids Promoted Formal Intramolecular [3+2] Parallel and Cross-Cycloadditions of Cyclopropane 1,1-Diesters with Allenes” Org. Lett. 2013, 15(22), 5682-5685.

22. Bo Cui, Jun Ren, Zhongwen Wang* “TfOH-catalyzed Formal [3+2] Cycloaddition of Cyclopropane 1,1-Diesters with Nitriles” J. Org. Chem. 2014, 79(02), 790-796.