周正洪
周正洪
博士 教授
周正洪,博士,教授,元素有机化学研究所,毕业于南开大学,四川绵阳江油市人。
工作内容:教学科研
人才称号:新世纪优秀人才支持计划入选者
通讯地址:天津市卫津路94号南开大学元素所合成楼419
电 话:23503891
电子邮件:z.h.zhou@nankai.edu.cn
课题组网站:
研究领域:不对称催化;杂原子有机化学
教育及科研经历:

1989–1993 四川师范学院化学系本科

1993-1998 南开大学元素所研究生

1998–至今 南开大学元素所

荣誉和奖励

2005年,中国化学会青年化学奖;

2005年,天津市自然科学三等奖;

2011年,入选教育部“新世纪优秀人才支持计划”

科研成果与代表作

1. C. Wang, Z. Zhou*, C. Tang, Novel bifunctional chiral thiourea catalyzed highly enantioselective aza-Henry reaction, Org. Lett. 2008, 10, 1707.

2. T. Liu, Y. Wang, G. Wu, H. Song, Z. Zhou*, C. Tang, Organocatalyzed enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinone to β,γ-unsaturated α-ketophosphonates, J. Org. Chem. 2011, 76, 4119.

3. R. Wu, X. Chang, A., Lu, Y. Wang, G. Wu, H. Song, Z. Zhou*, C. Tang, Chiral (thio)phosphorodiamides as excellent hydrogen bond donor catalysts in the asymmetric Michael addition of 2-hydroxy-1,4-naphthoquione to nitroolefins, Chem. Commun. 2011, 47, 5034.

4. A. Lu, T. Liu, R. Wu, Y. Wang, G. Wu, Z. Zhou*, J. Fang, C. Tang, A recyclable organocatalyst for asymmetric Michael addition of acetone to nitroolefins, J. Org. Chem. 2011, 76, 3872.

5. A. Lu, K. Hu, Y. Wang, H. Song, Z. Zhou*, J. Fang, C. Tang, Enantioselective Synthesis of trans-Dihydrobenzofurans via Primary Amine-Thiourea Organocatalyzed Intramolecular Michael Addition, J. Org. Chem. 2012, 77, 6208.

6. L. Wu, Y. Wang, H. Song, L. Tang, Z. Zhou*, C. Tang, Enantioselective organocatalytic domino Michael-aldol reactions: An efficient protocol to stereocontrolled construction of 2H-thiopyrano[2,3-b]quinolone scaffolds, Chem. Asian J. 2013, 2204.

7. H. Yu, Q. Wang, Y. Wang, H. Song, Z. Zhou*, C. Tang, Stereoselective Synthesis of Highly Functionalized Nitrocyclopropanes via Organocatalyic Michael Addition initiated cyclization of bromonitromethane and β,γ-unsaturated α-ketoesters, Chem. Asian J. 2013, 8, 2859.

8. L. Wu, Y. Wang, H. Song, L. Tang, Z. Zhou*, C. Tang, Synthesis of optically active 2H-thiopyrano[2,3-b]quinolines with three contiguous stereocenters via an organocatalytic asymmetric tandem Michael-Henry reaction, Adv. Synth. Catal. 2013, 355, 1053.

9. Y. Liu, Y. Wang, H. Song, Z. Zhou, C. Tang*, Asymmetric organocatalytic cascade Michael/hemiketalization/retro-aldol reaction of 2-((E)-2-nitrovinyl)phenols with 2,4-dioxo-4-arylbutanoates: A convenient access to chiral α-ketoesters, Adv. Synth. Catal. 2013, 355, 2544

10. L. Wu, Y. Wang, H. Song, L. Tang, Z. Zhou*, C. Tang, Organocatalyzed highly diastereo- and enantioselective tandem sulfa-Michael-Mannich reaction of 2-mercaptoquinoline-3-carbaldimines with maleimides, ChemCatChem 2014, 6, 649.

11. Y. Liu, Q. Wang, Y. Wang, H. Song, Z. Zhou*, Chiral Bifunctional Squaramide-Catalyzed Highly Enantioselective Michael Addition of Allomaltol to ,-Unsaturated -Ketoesters, ChemCatChem, 2014, 6, 2298.

12. Y. Zheng, Y. Wang, Z. Zhou*, Organocatalytic Multicomponent Synthesis of Polysubstituted Pyrroles from 1,2-diones, aldehydes and arylamines, Chem. Commun. 2015, 51, 11652.

13. Y. Wang, J. Pan, S. Chen, Y. Wang, Z. Zhou*, Sterercontrolled construction of 3,4-dihydrocoumarin scaffolds with a quaternary amino acid moiety via chiral squaramide catalyzed cascade Michael addition/lactonization reaction, Adv. Synth. Catal. 2016, 358, 195.

14. Y. Zheng, L. Cui, Y. Wang, Z. Zhou*, Stereocontrolled construction of tetrahydropyrano[2,3-c]pyrazole scaffold via an organocatalyzed formal [3+3] annulation, J. Org. Chem. 2016, 81, 4340.

15. S. Chen, Y. Wang, Z. Zhou*, Organocatalyzed Asymmetric Michael Addition of 1‑Acetylindolin-3-ones to β,γ-Unsaturated α-Ketoesters: An Access to Chiral Indolin-3-ones with Two Adjacent Tertiary Stereogenic Centers, J. Org. Chem. 2016, 81, 11432.

16. L. Cui, D. Lv, Y. Wang, Z. Li, Z. Fan, Z. Zhou*, Asymmetric formal [4 + 2] annulation of o‑quinone methides with β-keto acylpyrazoles: A general approach to optically active trans-3,4-dihydrocoumarins, J. Org. Chem. 2018, 83, 4221.

17. Y. Xiao, R. Jiang, Y. Wang, Z. Zhou*, Enantioselective construction of spiro thiazol-4-one derivatives with multiple stereocenters via an organocatalyzed multicomponent cascade reaction, Adv. Synth. Catal. 2018, 360, 1961.

18. L. Cui, Y. Wang, Z. Fan, Z. Li, Z. Zhou*, Kinetic resolution of axially chiral 2-nitrovinyl biaryls catalyzed by a bifunctional thiophosphinamide catalyst, Adv. Synth. Catal. 2019, 361, 3575.

人才培养

已培养博士4名,硕士30余名

教师办公管理系统 会议室预约系统 院级仪器管理平台 化学学院论文评审系统