1、复杂抗癌天然产物的全合成

2、基于复杂天然产物结构的药物化学

3、基于复杂天然产物靶点的药物化学

2011.6 获山东大学理学学士学位

2011.9-2013.9 南开大学 药学院 药物化学专业 硕转博（导师：陈悦）

2013.9-2016.7 南开大学 化学学院 有机化学专业 博士（导师：汤平平） 

2016.7-2018.12 南开大学药学院 讲师

2018.12-2020.10 南开大学药学院 副教授

2020.10-今 南开大学化学学院 副教授

国家自然科学基金青年项目：低氧靶向的抗胰腺癌天然产物BE-43547A2的构效关系研究 2018.1-2020.12 主持

国家自然科学基金面上项目：抗胰腺癌天然产物majusculamide D的构效关系研究2021.1-2024.12 主持

天津市创新人才推进计划优秀青年科技人才

南开大学百名青年学科带头人

1. Junhong Xiang, Yahui Ding*, Jiaxin Li, Xiuhe Zhao, Yuanjun Sun, Da Wang, Liang Wang*, and Yue Chen*, Ovatodiolides: Scalable Protection-free Syntheses, Configuration Determination and Biological Evaluation against Hepatic Cancer Stem Cells. Angew. Chem. Int. Ed., 2019, 131, 10697.

2.  Yuanjun Sun1, Yahui Ding1, Dongmei Li, Ruifei Zhou, Xiuwen Su, Juan Yang, Xiaoqian Guo, Chuanke Chong, Jinghan Wang, Weicheng Zhang, Cuigai Bai, Liang Wang*, Yue Chen*, Cyclic Depsipeptide BE-43547A2: Synthesis and Activity against Pancreatic Cancer Stem Cells. Angew. Chem. Int. Ed., 2017, 56, 14627. (Hot paper, Press Release Paper)

3. Liang Wang, Hengtao Wang, Yi Hang Li, and Pingping Tang*, Total Synthesis of Schilancitrilactones B and C. Angew. Chem. Int. Ed., 2015, 54, 5732.

4. Jinghan Wang, et al., Liang Wang*, Guang Yang*, Yue Chen*, Total Syntheses and Biological Activities of Vinylamycin Analogs. J. Med. Chem., 2017, 60, 1189. 

5.  Junhong Xiang, et al., Liang Wang*, Yue Chen*, Rapid Construction of the Scaffold of Quorumolide A Enabled by a Tandem ROM/RCM Strategy and a Tandem Oxidative Cyclization Strategy. Org. Lett., 2019, 21, 6485.

6. Baijun Ye, et al., Liang Wang*, Yue Chen*, Total Synthesis of the Highly N-Methylated Peptide Jahanyne. J. Org. Chem., 2018, 83, 6741.

7. Junhong Xiang, Xuemei Zhang, Dehong Wang, Jiaxin Li, Qiuying Li, Qin Wang, Yahui Ding*, Tianyang Chen, Yuanjun Sun, Shiqi Bao, Jing Chen, Dongmei Li, Liang Wang*, Yue Chen*, Chemical modification of ovatodiolide revealed a promising amino-prodrug with improved pharmacokinetic profile. Chem. Comm., 2020, 56, 11018.

已协助指导硕士研究生9名，博士研究生4名。