宋红健
宋红健
博士 其他

宋红健,博士,高级工程师,元素有机化学研究所,毕业于南开大学,山东滕州人。

工作内容:教学科研

人才称号:

通讯地址:天津市南开区卫津路94号元素所216

电 话:022-23503792

电子邮件:songhongjian@nankai.edu.cn
课题组网站:

http://skleoc.nankai.edu.cn/info/1018/3993.htm

研究领域:

天然源农药的分离、鉴定、全合成及结构优化;新型绿色农药的设计、合成、生物活性及构效关系研究。

教育及科研经历:

2008年本科毕业于曲阜师范大学,2011年和2014年分别获南开大学理学硕士和博士学位。2018年晋升为南开大学化学学院高级工程师;农药学硕士生导师,农业专硕导师。

荣誉和奖励

2020年荣获第四届赵善欢奖教基金优秀青年学术奖

科研成果与代表作

一直从事天然源抗植物病毒药物与绿色杀虫剂的创制研究,主持国家自然科学基金面上项目1项、青年项目1项,十四五国家重点研发计划子课题负责人1项,南开大学产学研用项目2项,人才培育项目2项;参与多项国家自然学基金面上项目和国家重点研发计划。创制了具有完全自主知识产权的超高效植物病毒病防治药剂和生态杀虫剂候选品种,正处于农药登记和产业开化的不同阶段。以一作或通讯联系人在J. Agric. Food Chem等国际农药化学领域权威期刊上发表论文45申请中国发明专利42项,PCT专利4项,授权美国专利2项及欧洲专利4项。

代表性论文

1. Guo, Zhonglin; Zhou, Pan; Song, Hongjian*; Liu, Yuxiu; Zhang, Jingjing*; Li, Yongqiang; Wang, Qingmin*. Design, Synthesis, and Bioactivities of Phthalide and Coumarin Derivatives Based on the Biosynthesis and Structure Simplification of Gossypol. J. Agric. Food Chem. 2021, 69, 15123-15135.

2. Yang, Yan; Liu, Yuxiu; Song, Hongjian;* Li, Yongqiang; Wang, Qingmin*. Design, Synthesis, and Insecticidal Activity of Novel Triazone Derivatives Containing Sulfonamide or Sulfonimide Moieties. J. Agric. Food Chem. 2021, 69, 10790−10796.

3. Wang, Ziwen; Ye, Fei; Feng, Yue; Xiao, Wen; Song, Hongjian; * Zhao, Li; Lu, Roujian; Huang, Baoying; Liu, Yuxiu; Wang, Wenling; Li, Yongqiang; Ding, Yi; Zheng, Yanlong; Song, Xiangrong;* Tan, Wenjie;* Wang Qingmin*. Discovery and Nanosized Preparations of (S,R)‑Tylophorine Malate as Novel anti-SARS-CoV‑2 Agents. ACS Med. Chem. Lett. 2021, 12, 1840−1846.

4. Wang, Haiqi; Song, Hongjian*. Synthesis, Configuration Determination, and Antiviral Activities of Four Optical Isomers of NK0209 as Plant Virus Disease Prevention and Control Drug Candidate, J. Agric. Food Chem. 2020, 68, 2631-2638.

5. Xie, Jialin; Xu, Wentao; Song, Hongjian*; Liu, Yuxiu; Zhang, Jingjing*; Wang, Qingmin*. Synthesis and Antiviral/Fungicidal/Insecticidal Activities Study of Novel Chiral Indole Diketopiperazine Derivatives Containing Acylhydrazone Moiety. J. Agric. Food Chem. 2020, 68, 5555−5571

6. Chen, Linwei; Hao, Yanke.; Song, Hongjian*; Liu, Yuxiu.; Li,Yongqiang; Zhang, Jingjing*; Qingmin Wang*. Design, Synthesis, Characterization, and Biological Activities of Novel Spirooxindole Analogues Containing Hydantoin, Thiohydantoin, Urea, and Thiourea Moieties. J. Agric. Food Chem. 2020, 68, 10618−10625.

7. Huang, Yuanqiong; Lv, Xueli; Song, Hongjian*; Liu, Yuxiu; Wang, Qingmin*. Rh(III)-catalyzed C8 arylation of quinoline N-oxides with arylboronic acids. Chin. Chem. Lett. 2020, 31 1572–1575.

8. Lyu, Xueli; Huang, Shisheng; Song, Hongjian*; Liu, Yuxiu*; Wang, Qingmin*. Visible-Light-Induced Copper-Catalyzed Decarboxylative Coupling of Redox-Active Esters with N-Heteroarenes. Org. Lett. 2019, 21,5728-5732.

9. Huang, Yuanqiong; Guo, Zhonglin; Song, Hongjian*; Liu, Yuxiu; Wang, Lizhong; Wang, Qingmin*. Design, Synthesis, and Biological Activity of beta-Carboline Analogues Containing Hydantoin, Thiohydantoin, and Urea Moieties. J. Agric. Food Chem. 2018, 66, 8253-8261.

10. Huang, Yuanqiong; Guo, Zhonglin; Song, Hongjian*; Liu, Yuxiu; Wang, Qingmin*. Silver-copper co-catalyzed cascade intramolecular cyclization/desulfinamide/dehydrogenation: one-pot synthesis of substituted carbazoles. Chem. Commun. 2018, 54, 7143-7146.

人才培养

协助汪清民教授指导博士3名、硕士15名。

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